ZNF365 gene

zinc finger protein 365

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes several isoforms which have different expression patterns and functions. Mutation in this gene is associated with uric acid nephrolithiasis (UAN). Alternatively spliced variants, encoding distinct proteins, have been identified. [provided by RefSeq, May 2010]

From UniProt: TALAN_HUMAN:

May play a role in uric acid excretion.

From NCBI Gene:

  • Uric acid nephrolithiasis, susceptibility to

From UniProt: TALAN_HUMAN:

Uric acid nephrolithiasis (UAN): A form of nephrolithiasis, a common multifactorial disease characterized by stones formation in the kidney and urinary tract. Nephrolithiasis is due to supersaturation of the urine by stone-forming constituents, including calcium, oxalate and uric acid. Crystals or foreign bodies can act as nidi, upon which ions from the supersaturated urine form microscopic crystalline structures. Uric acid nephrolithiasis occurs when the urine becomes overly concentrated with uric acid and accounts for 20% of all stones. [MIM:605990]

Cytogenetic Location: 10q21.2, which is the long (q) arm of chromosome 10 at position 21.2

Molecular Location: base pairs 62,373,609 to 62,672,011 on chromosome 10 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 10q21.2, which is the long (q) arm of chromosome 10 at position 21.2
  • Su48
  • UAN
  • ZNF365D