ZNF141 gene

zinc finger protein 141

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene is a zinc finger protein that may be a tumor suppressor. Defects in this gene have been associated with autosomal recessive postaxial polydactyly type A. [provided by RefSeq, Jan 2017]

From UniProt:

May be involved in transcriptional regulation as a repressor. Plays a role in limb development.

From NCBI Gene:

  • Postaxial polydactyly type A6

From UniProt:

Polydactyly, postaxial A6 (PAPA6): A condition characterized by the occurrence of supernumerary digits in the upper and/or lower extremities. In postaxial polydactyly type A, the extra digit is well-formed and articulates with the fifth or a sixth metacarpal/metatarsal. [MIM:615226]

Cytogenetic Location: 4p16.3, which is the short (p) arm of chromosome 4 at position 16.3

Molecular Location: base pairs 336,995 to 377,071 on chromosome 4 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 4p16.3, which is the short (p) arm of chromosome 4 at position 16.3
  • D4S90
  • pHZ-44