ZFAT gene

zinc finger and AT-hook domain containing

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009]

From UniProt:

May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated.

Cytogenetic Location: 8q24.22, which is the long (q) arm of chromosome 8 at position 24.22

Molecular Location: base pairs 134,477,788 to 134,713,049 on chromosome 8 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 8q24.22, which is the long (q) arm of chromosome 8 at position 24.22
  • AITD3
  • ZFAT1
  • ZNF406