WNT2 gene

Wnt family member 2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008]

From UniProt:

Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed:20018874). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons.

Cytogenetic Location: 7q31.2, which is the long (q) arm of chromosome 7 at position 31.2

Molecular Location: base pairs 117,276,631 to 117,323,289 on chromosome 7 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 7q31.2, which is the long (q) arm of chromosome 7 at position 31.2
  • INT1L1
  • IRP