VCY gene

variable charge, Y-linked

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene is a member of a family of human VCX/Y genes. This gene family has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. Members of the VCX/Y family share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. VCX/Y genes encode small and highly charged proteins of unknown function. This gene encodes a small, positively charged protein. The presence of a putative bipartite nuclear localization signal suggests that this gene encodes a nuclear protein. The genome has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy. [provided by RefSeq, Jul 2008]

From UniProt:

May mediate a process in spermatogenesis or may play a role in sex ratio distortion.

Cytogenetic Location: Yq11.221, which is the long (q) arm of the Y chromosome at position 11.221

Molecular Location: base pairs 13,985,772 to 13,986,512 on the Y chromosome (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: Yq11.221, which is the long (q) arm of the Y chromosome at position 11.221
  • BPY1
  • VCY1
  • VCY1A