USP45 gene

ubiquitin specific peptidase 45

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene is a deubiquitylase that binds ERCC1, the catalytic subunit of the XPF-ERCC1 DNA repair endonuclease. This endonuclease is a critical regulator of DNA repair processes, and the deubiquitylase activity of the encoded protein is important for maintaining the DNA repair ability of XPF-ERCC1. [provided by RefSeq, Sep 2016]

Cytogenetic Location: 6q16.2, which is the long (q) arm of chromosome 6 at position 16.2

Molecular Location: base pairs 99,432,306 to 99,515,770 on chromosome 6 (Homo sapiens Updated Annotation Release 109.20190905, GRCh38.p13) (NCBI)

Cytogenetic Location: 6q16.2, which is the long (q) arm of chromosome 6 at position 16.2