UGP2 gene

UDP-glucose pyrophosphorylase 2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

From UniProt:

Plays a central role as a glucosyl donor in cellular metabolic pathways.

From NCBI Gene:

  • EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 83

Cytogenetic Location: 2p15, which is the short (p) arm of chromosome 2 at position 15

Molecular Location: base pairs 63,840,969 to 63,891,562 on chromosome 2 (Homo sapiens Updated Annotation Release 109.20200522, GRCh38.p13) (NCBI)

Cytogenetic Location: 2p15, which is the short (p) arm of chromosome 2 at position 15
  • EIEE83
  • pHC379
  • SVUGP2
  • UDPG
  • UDPGP
  • UDPGP2
  • UGP1
  • UGPP1
  • UGPP2