TUBB8 gene

tubulin beta 8 class VIII

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene represents the primary beta-tubulin subunit of oocytes and the early embryo. Defects in this gene, which is primate-specific, are a cause of oocyte maturation defect 2 and infertility. [provided by RefSeq, Mar 2016]

From UniProt:

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

Cytogenetic Location: 10p15.3, which is the short (p) arm of chromosome 10 at position 15.3

Molecular Location: base pairs 46,437 to 49,504 on chromosome 10 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 10p15.3, which is the short (p) arm of chromosome 10 at position 15.3
  • bA631M21.2
  • OOMD
  • OOMD2