TSPY1 gene

testis specific protein, Y-linked 1

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene is found only in testicular tissue and may be involved in spermatogenesis. Many functional paralogs and pseudogenes of this gene are present in a cluster in humans, but only a single, nonfunctional orthologous gene is found in mouse. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

From UniProt:

May be involved in sperm differentiation and proliferation.

From UniProt:

TSPY is located in the gonadoblastoma critical region and is preferentially expressed in tumor germ cells of gonadoblastoma specimens. Expression also correlates with testicular seminoma and tumorigenesis of the prostate gland.

Cytogenetic Location: Yp11.2, which is the short (p) arm of the Y chromosome at position 11.2

Molecular Location: base pairs 9,466,955 to 9,469,756 on the Y chromosome (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: Yp11.2, which is the short (p) arm of the Y chromosome at position 11.2
  • CT78
  • DYS14
  • pJA923
  • TSPY