TRMT10A gene

tRNA methyltransferase 10A

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a protein that belongs to the tRNA (Guanine-1)-methyltransferase family. A similar gene in yeast modifies several different tRNA species. Mutations in this gene are associated with microcephaly, short stature, and impaired glucose metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

From UniProt:

RNA methyltransferase.

From NCBI Gene:

  • Microcephaly, short stature, and impaired glucose metabolism 1

From UniProt:

Microcephaly, short stature, and impaired glucose metabolism 1 (MSSGM1): A disease characterized by microcephaly, mental retardation, short stature, and disturbed glucose metabolism. Additional clinical features include delayed puberty, hypoglycemia-related seizures, hyperinsulinemic hypoglycemia, and early-onset diabetes. [MIM:616033]

Cytogenetic Location: 4q23, which is the long (q) arm of chromosome 4 at position 23

Molecular Location: base pairs 99,546,707 to 99,564,057 on chromosome 4 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 4q23, which is the long (q) arm of chromosome 4 at position 23
  • HEL-S-88
  • MSSGM
  • MSSGM1
  • RG9MTD2
  • TRM10