TRIM36 gene

tripartite motif containing 36

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

From UniProt:

E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in chromosome segregation and cell cycle regulation (PubMed:28087737). May play a role in the acrosome reaction and fertilization.

From NCBI Gene:

  • Anencephalus

From UniProt:

Anencephaly (ANPH): An extreme form of neural tube defect resulting in the absence of brain tissues, and death in utero or perinatally. Infants are born with intact spinal cords, cerebellums, and brainstems, but lack formation of neural structures above this level. The skull is only partially formed. ANPH inheritance is autosomal recessive. [MIM:206500]

Cytogenetic Location: 5q22.3, which is the long (q) arm of chromosome 5 at position 22.3

Molecular Location: base pairs 115,124,762 to 115,180,546 on chromosome 5 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 5q22.3, which is the long (q) arm of chromosome 5 at position 22.3
  • ANPH
  • HAPRIN
  • RBCC728
  • RNF98