TREH gene

trehalase

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes an enzyme that hydrolyses trehalose, a disaccharide formed from two glucose molecules found mainly in fungi, plants, and insects. A partial duplication of this gene is located adjacent to this locus on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

From UniProt:

Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose.

From NCBI Gene:

  • alpha, alpha-Trehalase deficiency

From UniProt:

Trehalase deficiency (TREHD): An autosomal recessive condition characterized by the inability to digest trehalose, a disaccharide found in mushrooms, products containing baker's yeast, and dried food. Individuals with trehalase deficiency suffer from abdominal pain, increased rectal flatulence, and diarrhea due to osmotic water flow into the colon. [MIM:612119]

Cytogenetic Location: 11q23.3, which is the long (q) arm of chromosome 11 at position 23.3

Molecular Location: base pairs 118,658,232 to 118,679,672 on chromosome 11 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 11q23.3, which is the long (q) arm of chromosome 11 at position 23.3
  • TRE
  • TREA
  • TREHD