TOR1AIP1 gene

torsin 1A interacting protein 1

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a type 2 integral membrane protein that binds A- and B-type lamins. The encoded protein localizes to the inner nuclear membrane and may be involved in maintaining the attachment of the nuclear membrane to the nuclear lamina during cell division. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2016]

From UniProt:

Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.

Cytogenetic Location: 1q25.2, which is the long (q) arm of chromosome 1 at position 25.2

Molecular Location: base pairs 179,882,042 to 179,920,077 on chromosome 1 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 1q25.2, which is the long (q) arm of chromosome 1 at position 25.2
  • LAP1
  • LAP1B
  • LGMD2Y