TENM4 gene

teneurin transmembrane protein 4

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene plays a role in establishing proper neuronal connectivity during development. Defects in this gene have been associated with hereditary essential tremor-5. [provided by RefSeq, Oct 2016]

From UniProt:

Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Plays a role in the establishment of the anterior-posterior axis during gastrulation. Regulates the differentiation and cellular process formation of oligodendrocytes and myelination of small-diameter axons in the central nervous system (CNS) (PubMed:26188006). Promotes activation of focal adhesion kinase. May function as a cellular signal transducer.

From NCBI Gene:

  • Tremor, hereditary essential, 5

From UniProt:

Tremor, hereditary essential 5 (ETM5): A common movement disorder mainly characterized by postural tremor of the arms. Head, legs, trunk, voice, jaw, and facial muscles also may be involved. The condition can be aggravated by emotions, hunger, fatigue and temperature extremes, and may cause a functional disability or even incapacitation. Inheritance is autosomal dominant. [MIM:616736]

Cytogenetic Location: 11q14.1, which is the long (q) arm of chromosome 11 at position 14.1

Molecular Location: base pairs 78,653,283 to 79,441,019 on chromosome 11 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 11q14.1, which is the long (q) arm of chromosome 11 at position 14.1
  • Doc4
  • ETM5
  • ODZ4
  • ten-4
  • Ten-M4
  • TNM4