TBR1 gene

T-box, brain 1

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of numerous developmental processes. In mouse, the ortholog of this gene is expressed in the cerebral cortex, hippocampus, amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection. In mouse, the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. [provided by RefSeq, Dec 2015]

From UniProt:

Probable transcriptional regulator involved in developmental processes. Required for normal brain development.

Cytogenetic Location: 2q24.2, which is the long (q) arm of chromosome 2 at position 24.2

Molecular Location: base pairs 161,416,094 to 161,425,867 on chromosome 2 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 2q24.2, which is the long (q) arm of chromosome 2 at position 24.2
  • TBR-1
  • TES-56