TBC1D32 gene

TBC1 domain family member 32

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a TBC-domain containing protein. Studies of a similar protein in mouse and zebrafish suggest that the encoded protein is involved in sonic hedgehog signaling, and that it interacts with and stabilizes cell cycle-related kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

From UniProt:

Required for high-level Shh responses in the developing neural tube. Together with CDK20, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to Shh signaling.

Cytogenetic Location: 6q22.31, which is the long (q) arm of chromosome 6 at position 22.31

Molecular Location: base pairs 121,079,494 to 121,335,384 on chromosome 6 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 6q22.31, which is the long (q) arm of chromosome 6 at position 22.31
  • bA57L9.1
  • bA301B7.2
  • BROMI
  • C6orf170
  • C6orf171
  • dJ310J6.1