TACSTD2 gene

tumor-associated calcium signal transducer 2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009]

From UniProt:

May function as a growth factor receptor.

From NCBI Gene:

  • Lattice corneal dystrophy Type III

From UniProt:

Corneal dystrophy, gelatinous drop-like (GDLD): A form of lattice corneal dystrophy, a class of inherited stromal amyloidoses characterized by pathognomonic branching lattice figures in the cornea. GDLD is an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. Clinical manifestations, which appear in the first decade of life, include blurred vision, photophobia, and foreign-body sensation. By the third decade, raised, yellowish-gray, gelatinous masses severely impair visual acuity. [MIM:204870]

Cytogenetic Location: 1p32, which is the short (p) arm of chromosome 1 at position 32

Molecular Location: base pairs 58,575,423 to 58,577,494 on chromosome 1 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 1p32, which is the short (p) arm of chromosome 1 at position 32
  • EGP-1
  • EGP1
  • GA733-1
  • GA7331
  • GP50
  • M1S1
  • TROP2