TACO1

translational activator of cytochrome c oxidase I

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a mitochondrial protein that function as a translational activator of mitochondrially-encoded cytochrome c oxidase 1. Mutations in this gene are associated with Leigh syndrome.[provided by RefSeq, Mar 2010]

From UniProt:

Acts as a translational activator of mitochondrially-encoded cytochrome c oxidase 1.

Covered on Genetics Home Reference:

From NCBI Gene:

  • Cytochrome-c oxidase deficiency

From UniProt:

Leigh syndrome (LS): An early-onset progressive neurodegenerative disorder characterized by the presence of focal, bilateral lesions in one or more areas of the central nervous system including the brainstem, thalamus, basal ganglia, cerebellum and spinal cord. Clinical features depend on which areas of the central nervous system are involved and include subacute onset of psychomotor retardation, hypotonia, ataxia, weakness, vision loss, eye movement abnormalities, seizures, and dysphagia. [MIM:256000]

Cytogenetic Location: 17q23.3, which is the long (q) arm of chromosome 17 at position 23.3

Molecular Location: base pairs 63,600,872 to 63,608,365 on chromosome 17 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 17q23.3, which is the long (q) arm of chromosome 17 at position 23.3
  • CCDC44