SUN5 gene

Sad1 and UNC84 domain containing 5

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene appears to play a role in the meiotic stage of spermatogenesis. The encoded protein localizes to the junction between the sperm head and body and may be involved in nuclear envelope reconstitution and nuclear migration. Mutations in this gene have been implicated in acephalic spermatozoa syndrome. [provided by RefSeq, May 2017]

From UniProt:

May be involved in meiotic stage of spermatogenesis.

From NCBI Gene:

  • SPERMATOGENIC FAILURE 16

From UniProt:

Spermatogenic failure 16 (SPGF16): An infertility disorder caused by spermatogenesis defects and characterized by abnormally shaped spermatozoa in the semen of affected individuals. Most spermatozoa are made up of headless tails, while a small proportion has an abnormal head-tail junction. A few spermatozoa are made up of tailless heads. [MIM:617187]

Cytogenetic Location: 20q11.21, which is the long (q) arm of chromosome 20 at position 11.21

Molecular Location: base pairs 32,983,773 to 33,004,449 on chromosome 20 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 20q11.21, which is the long (q) arm of chromosome 20 at position 11.21
  • dJ726C3.1
  • SPAG4L
  • SPGF16
  • TSARG4