STAG1 gene

stromal antigen 1

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase. [provided by RefSeq, Jul 2008]

From UniProt:

Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.

Cytogenetic Location: 3q22.3, which is the long (q) arm of chromosome 3 at position 22.3

Molecular Location: base pairs 136,336,235 to 136,752,412 on chromosome 3 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 3q22.3, which is the long (q) arm of chromosome 3 at position 22.3
  • MRD47
  • SA1
  • SCC3A