SPINK2 gene

serine peptidase inhibitor, Kazal type 2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a member of the family of serine protease inhibitors of the Kazal type (SPINK). The encoded protein acts as a trypsin and acrosin inhibitor in the genital tract and is localized in the spermatozoa. The protein has been associated with the progression of lymphomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

From UniProt:

Strong inhibitor of acrosin in male and/or female genital tract. Also inhibits trypsin.

Cytogenetic Location: 4q12, which is the long (q) arm of chromosome 4 at position 12

Molecular Location: base pairs 56,809,860 to 56,822,210 on chromosome 4 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 4q12, which is the long (q) arm of chromosome 4 at position 12
  • HUSI-II
  • SPGF29