SOX11 gene

SRY-box 11

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. [provided by RefSeq, Jul 2008]

From UniProt:

Transcriptional factor involved in the embryonic neurogenesis. May also have a role in tissue modeling during development.

From NCBI Gene:

  • Mental retardation, autosomal dominant 27

From UniProt:

Mental retardation, autosomal dominant 27 (MRD27): A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. MRD27 patients show dysmorphic facial features, microcephaly, growth deficiency, hypoplastic fifth toenails, and mild intellectual disability. [MIM:615866]

Cytogenetic Location: 2p25.2, which is the short (p) arm of chromosome 2 at position 25.2

Molecular Location: base pairs 5,692,667 to 5,701,385 on chromosome 2 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 2p25.2, which is the short (p) arm of chromosome 2 at position 25.2