SLMAP gene

sarcolemma associated protein

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a component of a conserved striatin-interacting phosphatase and kinase complex. Striatin family complexes participate in a variety of cellular processes including signaling, cell cycle control, cell migration, Golgi assembly, and apoptosis. The protein encoded by this gene is a coiled-coil, tail-anchored membrane protein with a single C-terminal transmembrane domain that is posttranslationally inserted into membranes. Mutations in this gene are associated with Brugada syndrome, a cardiac channelopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

From UniProt:

May play a role during myoblast fusion.

Cytogenetic Location: 3p21.2-p14.3, which is the short (p) arm of chromosome 3 between positions 21.2 and 14.3

Molecular Location: base pairs 57,756,221 to 57,930,013 on chromosome 3 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 3p21.2-p14.3, which is the short (p) arm of chromosome 3 between positions 21.2 and 14.3