SLCO2A1 gene

solute carrier organic anion transporter family member 2A1

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a prostaglandin transporter that is a member of the 12-membrane-spanning superfamily of transporters. The encoded protein may be involved in mediating the uptake and clearance of prostaglandins in numerous tissues. [provided by RefSeq, Dec 2011]

From UniProt:

May mediate the release of newly synthesized prostaglandins from cells, the transepithelial transport of prostaglandins, and the clearance of prostaglandins from the circulation. Transports PGD2, as well as PGE1, PGE2 and PGF2A.

From NCBI Gene:

  • Primary hypertrophic osteoarthropathy, autosomal recessive 2

From UniProt:

Hypertrophic osteoarthropathy, primary, autosomal recessive, 2 (PHOAR2): A disease characterized by digital clubbing, periostosis, acroosteolysis, painful joint enlargement, and variable features of pachydermia that include thickened facial skin and a thickened scalp. Other developmental anomalies include delayed closure of the cranial sutures and congenital heart disease. [MIM:614441]

Cytogenetic Location: 3q21, which is the long (q) arm of chromosome 3 at position 21

Molecular Location: base pairs 133,932,696 to 134,030,076 on chromosome 3 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 3q21, which is the long (q) arm of chromosome 3 at position 21
  • MATR1
  • OATP2A1
  • PGT
  • PHOAR2
  • SLC21A2