SLC9A1 gene

solute carrier family 9 member A1

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a Na+/H+ antiporter that is a member of the solute carrier family 9. The encoded protein is a plasma membrane transporter that is expressed in the kidney and intestine. This protein plays a central role in regulating pH homeostasis, cell migration and cell volume. This protein may also be involved in tumor growth. [provided by RefSeq, Sep 2011]

From UniProt:

Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.

From NCBI Gene:

  • Lichtenstein-knorr syndrome

From UniProt:

Lichtenstein-Knorr syndrome (LIKNS): An autosomal recessive neurologic disorder characterized by progressive cerebellar ataxia and severe progressive sensorineural hearing loss. [MIM:616291]

Cytogenetic Location: 1p36.1-p35, which is the short (p) arm of chromosome 1 between positions 36.1 and 35

Molecular Location: base pairs 27,098,809 to 27,155,130 on chromosome 1 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 1p36.1-p35, which is the short (p) arm of chromosome 1 between positions 36.1 and 35
  • APNH
  • LIKNS
  • NHE-1
  • NHE1
  • PPP1R143