SLC30A2 gene

solute carrier family 30 member 2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene is a zinc transporter that acts as a homodimer. The encoded protein plays a role in secreting zinc into breast milk. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

From NCBI Gene:

  • Zinc deficiency, transient neonatal

From UniProt:

Zinc deficiency, transient neonatal (TNZD): A disorder occurring in breast-fed infants as a consequence of low milk zinc concentration in their nursing mothers, which cannot be corrected by maternal zinc supplementation. A large amount of zinc, an essential trace mineral, is required for normal growth particularly in infants, and breast milk normally contains adequate zinc to meet the requirement for infants up to 4 to 6 months of age. Zinc deficiency can lead to dermatitis, alopecia, decreased growth, and impaired immune function. The disorder shows autosomal dominant inheritance with incomplete penetrance. [MIM:608118]

Cytogenetic Location: 1p35.3, which is the short (p) arm of chromosome 1 at position 35.3

Molecular Location: base pairs 26,038,022 to 26,046,138 on chromosome 1 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 1p35.3, which is the short (p) arm of chromosome 1 at position 35.3
  • PP12488
  • TNZD
  • ZnT-2
  • ZNT2