SLC24A4 gene
solute carrier family 24 member 4
The information on this page was automatically extracted from online scientific databases.
From NCBI Gene:
This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]
From UniProt:
Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons (OSNs) which subsequently influences how odor information is encoded and perceived. May play a role in calcium transport during amelogenesis (By similarity).
Related Information
Covered on Genetics Home Reference:
From NCBI Gene:
- Amelogenesis imperfecta, hypomaturation type IIA5
- Skin/hair/eye pigmentation, variation in, 6
From UniProt:
Amelogenesis imperfecta, hypomaturation type, 2A5 (AI2A5): A defect of enamel formation. The disorder involves both primary and secondary dentitions. The teeth have a shiny agar jelly appearance and the enamel is softer than normal. Brown pigment is present in middle layers of enamel. [MIM:615887]
Related Information
Cytogenetic Location: 14q32.12, which is the long (q) arm of chromosome 14 at position 32.12
Molecular Location: base pairs 92,322,581 to 92,501,481 on chromosome 14 (Homo sapiens Updated Annotation Release 109.20190905, GRCh38.p13) (NCBI)

Related Information
- AI2A5
- NCKX4
- SHEP6
- SLC24A2