SLC18A2 gene

solute carrier family 18 member A2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes an transmembrane protein that functions as an ATP-dependent transporter of monoamines, such as dopamine, norepinephrine, serotonin, and histamine. This protein transports amine neurotransmitters into synaptic vesicles. Polymorphisms in this gene may be associated with schizophrenia, bipolar disorder, and other neurological/psychiatric ailments. [provided by RefSeq, Jun 2018]

From UniProt:

Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis.

Cytogenetic Location: 10q25.3, which is the long (q) arm of chromosome 10 at position 25.3

Molecular Location: base pairs 117,241,073 to 117,279,430 on chromosome 10 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 10q25.3, which is the long (q) arm of chromosome 10 at position 25.3
  • PKDYS2
  • SVAT
  • SVMT
  • VAT2
  • VMAT2