SHROOM3 gene

shroom family member 3

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a PDZ-domain-containing protein that belongs to a family of Shroom-related proteins. This protein may be involved in regulating cell shape in certain tissues. A similar protein in mice is required for proper neurulation. [provided by RefSeq, Jan 2011]

From UniProt:

Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers. Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays.

Cytogenetic Location: 4q21.1, which is the long (q) arm of chromosome 4 at position 21.1

Molecular Location: base pairs 76,435,100 to 76,783,253 on chromosome 4 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 4q21.1, which is the long (q) arm of chromosome 4 at position 21.1
  • APXL3
  • MSTP013
  • SHRM
  • ShrmL