SEPT12 gene

septin 12

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

From UniProt:

Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis .

From NCBI Gene:

  • Spermatogenic failure 10

From UniProt:

Spermatogenic failure 10 (SPGF10): An infertility disorder caused by spermatogenesis defects. It results in decreased sperm motility, concentration, and multiple sperm structural defects. The most prominent feature is a defective sperm annulus, a ring structure that demarcates the midpiece and the principal piece of the sperm tail. [MIM:614822]

Cytogenetic Location: 16p13.3, which is the short (p) arm of chromosome 16 at position 13.3

Molecular Location: base pairs 4,777,602 to 4,791,610 on chromosome 16 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 16p13.3, which is the short (p) arm of chromosome 16 at position 13.3
  • SPGF10