RXFP2 gene

relaxin/insulin like family peptide receptor 2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]

From UniProt:

Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).

From NCBI Gene:

  • Cryptorchidism, unilateral or bilateral

From UniProt:

Cryptorchidism (CRYPTO): One of the most frequent congenital abnormalities in humans, involving 2-5% of male births. Cryptorchidism is associated with increased risk of infertility and testicular cancer. [MIM:219050]

Cytogenetic Location: 13q13.1, which is the long (q) arm of chromosome 13 at position 13.1

Molecular Location: base pairs 31,739,542 to 31,802,872 on chromosome 13 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 13q13.1, which is the long (q) arm of chromosome 13 at position 13.1
  • GPR106
  • GREAT
  • INSL3R
  • LGR8
  • LGR8.1
  • RXFPR2