RNPC3 gene

RNA binding region (RNP1, RRM) containing 3

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome. [provided by RefSeq, Jul 2008]

From UniProt:

Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA.

From NCBI Gene:

  • ISOLATED GROWTH HORMONE DEFICIENCY, TYPE V

Cytogenetic Location: 1p21.1, which is the short (p) arm of chromosome 1 at position 21.1

Molecular Location: base pairs 103,525,956 to 103,555,239 on chromosome 1 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 1p21.1, which is the short (p) arm of chromosome 1 at position 21.1
  • IGHD5
  • RBM40
  • RNP
  • SNRNP65