RNASET2 gene

ribonuclease T2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This ribonuclease gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement. [provided by RefSeq, Jul 2008]

From UniProt:

Has ribonuclease activity, with higher activity at acidic pH. Probably is involved in lysosomal degradation of ribosomal RNA (By similarity). Probably plays a role in cellular RNA catabolism.

From NCBI Gene:

  • Leukoencephalopathy, cystic, without megalencephaly

From UniProt:

Leukoencephalopathy, cystic, without megalencephaly (LCWM): An infantile-onset syndrome of cerebral leukoencephalopathy. Affected newborns develop microcephaly and neurologic abnormalities including psychomotor impairment, seizures and sensorineural hearing impairment. The brain shows multifocal white matter lesions, anterior temporal lobe subcortical cysts, pericystic abnormal myelination, ventriculomegaly and intracranial calcifications. [MIM:612951]

Cytogenetic Location: 6q27, which is the long (q) arm of chromosome 6 at position 27

Molecular Location: base pairs 166,929,509 to 166,956,589 on chromosome 6 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 6q27, which is the long (q) arm of chromosome 6 at position 27
  • bA514O12.3
  • RNASE6PL