PWRN1 gene

Prader-Willi region non-protein coding RNA 1

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene is located in the Prader-Willi syndrome (PWS) region of chromosome 15, which is known to undergo imprinting. The transcript is believed to be non-coding. It is bi-allelically expressed in testis and kidney, but mono-allelically expressed from the paternal allele in brain. This gene is poly-adenylated and is known to undergo alternative splicing. Transcript variants may represent part of a complex imprinting center-SNURF-SNRPN transcription unit. The contribution of this gene to the PWS phenotype is unknown, but it has been suggested that it may play a role in establishing paternal imprinting in the PWS region, perhaps by maintaining the paternal allele in an open chromatin configuration. [provided by RefSeq, Sep 2009]

Cytogenetic Location: 15q11.2, which is the long (q) arm of chromosome 15 at position 11.2

Molecular Location: base pairs 24,558,157 to 24,587,780 on chromosome 15 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 15q11.2, which is the long (q) arm of chromosome 15 at position 11.2
  • NCRNA00198