PTPRZ1 gene

protein tyrosine phosphatase, receptor type Z1

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]

From UniProt:

Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades.

From NCBI Gene:

  • Helicobacter pylori infection, susceptibility to

Cytogenetic Location: 7q31.32, which is the long (q) arm of chromosome 7 at position 31.32

Molecular Location: base pairs 121,873,105 to 122,062,036 on chromosome 7 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 7q31.32, which is the long (q) arm of chromosome 7 at position 31.32
  • HPTPZ
  • HPTPzeta
  • phosphacan
  • PTP-ZETA
  • PTP18
  • PTPRZ
  • PTPZ
  • R-PTP-zeta-2
  • RPTPB
  • RPTPbeta