PTGER2 gene

prostaglandin E receptor 2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. [provided by RefSeq, Oct 2009]

From UniProt:

Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.

From NCBI Gene:

  • Asthma, nasal polyps, and aspirin intolerance

Cytogenetic Location: 14q22.1, which is the long (q) arm of chromosome 14 at position 22.1

Molecular Location: base pairs 52,314,298 to 52,328,606 on chromosome 14 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 14q22.1, which is the long (q) arm of chromosome 14 at position 22.1