PNPLA4 gene

patatin like phospholipase domain containing 4

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a member of the patatin-like family of phospholipases. The encoded enzyme has both triacylglycerol lipase and transacylase activities and may be involved in adipocyte triglyceride homeostasis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome Y. [provided by RefSeq, Feb 2010]

From UniProt:

Lipid hydrolase.

From UniProt:

Defects in PNPLA4 may play a role in mitochondrial disorders characterized by complex IV deficiency.

Cytogenetic Location: Xp22.3, which is the short (p) arm of the X chromosome at position 22.3

Molecular Location: base pairs 7,898,763 to 7,928,587 on the X chromosome (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: Xp22.3, which is the short (p) arm of the X chromosome at position 22.3
  • DXS1283E
  • GS2
  • iPLA2eta