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Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
Covered on Genetics Home Reference:
Cytogenetic Location: 3p21.31, which is the short (p) arm of chromosome 3 at position 21.31
Molecular Location: base pairs 48,403,854 to 48,430,324 on chromosome 3 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)
Published: August 15, 2017
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