PLS1 gene

plastin 1

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The protein encoded by this gene is a third distinct plastin isoform, which is specifically expressed at high levels in the small intestine. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Feb 2010]

From UniProt:

Actin-bundling protein in the absence of calcium.

Cytogenetic Location: 3q23, which is the long (q) arm of chromosome 3 at position 23

Molecular Location: base pairs 142,596,393 to 142,713,664 on chromosome 3 (Homo sapiens Updated Annotation Release 109.20200522, GRCh38.p13) (NCBI)

Cytogenetic Location: 3q23, which is the long (q) arm of chromosome 3 at position 23
  • DFNA76