PLPBP gene

pyridoxal phosphate binding protein

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a pyridoxal 5'-phosphate binding protein involved in the homeostatic regulation of intracellular pyridoxal 5'-phosphate. This gene has a tumor suppressive effect on hepatocellular carcinoma and other solid tumors of epithelial origin. Naturally occurring mutations in this gene are associated with a pyridoxine-dependent epilepsy. [provided by RefSeq, Mar 2017]

From NCBI Gene:

  • EPILEPSY, EARLY-ONSET, VITAMIN B6-DEPENDENT

Cytogenetic Location: 8p11.23, which is the short (p) arm of chromosome 8 at position 11.23

Molecular Location: base pairs 37,761,753 to 37,779,768 on chromosome 8 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 8p11.23, which is the short (p) arm of chromosome 8 at position 11.23
  • EPVB6D
  • PROSC