PLD1 gene

phospholipase D1

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. [provided by RefSeq, Sep 2011]

From UniProt:

Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic.

Cytogenetic Location: 3q26.31, which is the long (q) arm of chromosome 3 at position 26.31

Molecular Location: base pairs 171,600,404 to 171,810,494 on chromosome 3 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 3q26.31, which is the long (q) arm of chromosome 3 at position 26.31