PIGH gene

phosphatidylinositol glycan anchor biosynthesis class H

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. The protein encoded by this gene is a subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. [provided by RefSeq, Jul 2008]

From UniProt:

Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

From NCBI Gene:

  • GLYCOSYLPHOSPHATIDYLINOSITOL BIOSYNTHESIS DEFECT 17

Cytogenetic Location: 14q24.1, which is the long (q) arm of chromosome 14 at position 24.1

Molecular Location: base pairs 67,589,306 to 67,600,302 on chromosome 14 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 14q24.1, which is the long (q) arm of chromosome 14 at position 24.1