PDE4DIP gene

phosphodiesterase 4D interacting protein

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene serves to anchor phosphodiesterase 4D to the Golgi/centrosome region of the cell. Defects in this gene may be a cause of myeloproliferative disorder (MBD) associated with eosinophilia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]

From UniProt:

May function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes.

From UniProt:

A chromosomal aberration involving PDE4DIP may be the cause of a myeloproliferative disorder (MBD) associated with eosinophilia. Translocation t(1;5)(q23;q33) that forms a PDE4DIP-PDGFRB fusion protein.

Cytogenetic Location: 1q12, which is the long (q) arm of chromosome 1 at position 12

Molecular Location: base pairs 148,808,167 to 149,051,277 on chromosome 1 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 1q12, which is the long (q) arm of chromosome 1 at position 12
  • CMYA2
  • MMGL