PAX4 gene

paired box 4

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells. [provided by RefSeq, Jul 2008]

From NCBI Gene:

  • Diabetes mellitus, ketosis-prone
  • Diabetes mellitus type 2
  • Maturity-onset diabetes of the young, type 9

Cytogenetic Location: 7q32.1, which is the long (q) arm of chromosome 7 at position 32.1

Molecular Location: base pairs 127,610,292 to 127,618,142 on chromosome 7 (Homo sapiens Updated Annotation Release 109.20190905, GRCh38.p13) (NCBI)

Cytogenetic Location: 7q32.1, which is the long (q) arm of chromosome 7 at position 32.1
  • KPD
  • MODY9