OPRD1 gene
opioid receptor delta 1
The information on this page was automatically extracted from online scientific databases.
From UniProt:
G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
Related Information
Covered on Genetics Home Reference:
Related Information
Cytogenetic Location: 1p35.3, which is the short (p) arm of chromosome 1 at position 35.3
Molecular Location: base pairs 28,812,142 to 28,863,696 on chromosome 1 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Related Information
- DOP
- DOR
- DOR1
- OPRD