NUP37 gene

nucleoporin 37

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

Nuclear pore complexes (NPCs) are used for transporting macromolecules between the cytoplasm and the nucleus. NPCs consist of multiple copies of 30 distinct proteins (nucleoporins), which assemble into biochemically-separable subcomplexes. The protein encoded by this gene is part of a subcomplex (Nup107-160) that is required for proper NPC function as well as for normal kinetochore-microtubule interaction and mitosis. [provided by RefSeq, Dec 2015]

From UniProt:

Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.

From NCBI Gene:

  • MICROCEPHALY 24, PRIMARY, AUTOSOMAL RECESSIVE

Cytogenetic Location: 12q23.2, which is the long (q) arm of chromosome 12 at position 23.2

Molecular Location: base pairs 102,073,962 to 102,120,131 on chromosome 12 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 12q23.2, which is the long (q) arm of chromosome 12 at position 23.2
  • MCPH24
  • p37