NTF4 gene

neurotrophin 4

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood. [provided by RefSeq, Jul 2008]

From UniProt:

Target-derived survival factor for peripheral sensory sympathetic neurons.

From NCBI Gene:

  • Glaucoma 1, open angle, O

From UniProt:

Glaucoma 1, open angle, O (GLC1O): A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. However, glaucoma can occur at any intraocular pressure. The disease is generally asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place. [MIM:613100]

Cytogenetic Location: 19q13.3, which is the long (q) arm of chromosome 19 at position 13.3

Molecular Location: base pairs 49,058,284 to 49,065,076 on chromosome 19 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 19q13.3, which is the long (q) arm of chromosome 19 at position 13.3
  • GLC1O
  • GLC10
  • NT-4
  • NT-4/5
  • NT-5
  • NT4
  • NT5
  • NTF5