NR2F2 gene

nuclear receptor subfamily 2 group F member 2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

From UniProt:

Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A.

From NCBI Gene:

  • Congenital heart defects, multiple types, 4

From UniProt:

Congenital heart defects, multiple types, 4 (CHTD4): A disorder characterized by congenital developmental abnormalities involving structures of the heart. Common defects include transposition of the great arteries, aortic stenosis, atrial septal defect, ventricular septal defect, pulmonic stenosis, and patent ductus arteriosus. Some patients also have cardiac arrhythmias, which may be due to the anatomic defect itself or to surgical interventions. [MIM:615779]

Cytogenetic Location: 15q26, which is the long (q) arm of chromosome 15 at position 26

Molecular Location: base pairs 96,325,928 to 96,340,263 on chromosome 15 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 15q26, which is the long (q) arm of chromosome 15 at position 26
  • ARP1
  • CHTD4
  • COUPTFB
  • COUPTFII
  • NF-E3
  • NR2F1
  • SVP40
  • TFCOUP2