NLGN1 gene

neuroligin 1

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. [provided by RefSeq, Jul 2008]

From UniProt:

Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Required to maintain wakefulness quality and normal synchrony of cerebral cortex activity during wakefulness and sleep.

Cytogenetic Location: 3q26.31, which is the long (q) arm of chromosome 3 at position 26.31

Molecular Location: base pairs 173,395,929 to 174,294,372 on chromosome 3 (Homo sapiens Updated Annotation Release 109.20200522, GRCh38.p13) (NCBI)

Cytogenetic Location: 3q26.31, which is the long (q) arm of chromosome 3 at position 26.31