NFIA gene

nuclear factor I A

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

From UniProt:

Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

From NCBI Gene:

  • Brain malformations and urinary tract defects

From UniProt:

Brain malformations and urinary tract defects (BRMUTD): A syndrome characterized by corpus callosum hypoplasia or agenesis, hydrocephalus or ventricular enlargement, developmental delay, and urinary tract defects. [MIM:613735]

Cytogenetic Location: 1p31.3, which is the short (p) arm of chromosome 1 at position 31.3

Molecular Location: base pairs 61,077,124 to 61,462,788 on chromosome 1 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 1p31.3, which is the short (p) arm of chromosome 1 at position 31.3
  • BRMUTD
  • CTF
  • NF-I/A
  • NF1-A
  • NFI-A
  • NFI-L